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TESAMORELIN

TESAMORELIN

Price range: $65.00 through $180.00

Research Use Only

All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Tesamorelin Overview

Tesamorelin is a synthetic analog of GHRH, designed to modulate somatotroph axis signaling. In preclinical and experimental research, it has been studied for its ability to influence endocrine pathway activity, regulate downstream cascades, and support investigations into systemic signaling dynamics.

Falutz J. et al. (2010).

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History

Tesamorelin was developed through research into GHRH peptides, building on discoveries that synthetic analogs could prolong the half-life and activity of native GHRH fragments. It was synthesized in the late 1990s and early 2000s as a stabilized peptide with improved pharmacokinetic properties, allowing for sustained endocrine pathway activation in experimental models. Research expanded into its effects on downstream signaling and systemic function, where it has remained an important tool in laboratory and preclinical studies.

Gertner J.M. et al. (2002).

Tesamorelin Structure

CAS #: 901758-09-6

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight: ~5135.9 g/mol

PubChem ID: 16132314

Research Findings

Tesamorelin has been studied in endocrine, signaling, and molecular models, with research highlighting its activity in somatotroph axis modulation, downstream cascades, pathway dynamics, and protein synthesis pathways. Studies also report effects on lipid pathway signaling, endocrine markers, and molecular proliferation in preclinical systems.

Key Areas of Research:

  • Endocrine: Somatotroph axis, signaling, cascades

  • Signaling: Lipid pathways, dynamics, markers

  • Molecular: Proliferation, remodeling, protein synthesis

Together, these findings suggest broad experimental potential for Tesamorelin across endocrine, signaling, and molecular pathways. By modulating somatotroph axis activity and influencing downstream cascades and protein synthesis processes, Tesamorelin provides a versatile research platform for exploring molecular remodeling, pathway characterization, and endocrine biology in laboratory settings.

Falutz J. et al., 2010

References

Falutz J. et al. (2010). Effects of Tesamorelin, a GHRH analog, on visceral fat in research studies. N Engl J Med, 362(6): 520–531.

Allas S. et al. (2011). Metabolic effects of Tesamorelin in research populations. J Clin Endocrinol Metab, 96(1): 13–22.

Gertner J.M. et al. (2002). Pharmacokinetics and endocrine effects of Tesamorelin, a stabilized GHRH analog. J Clin Endocrinol Metab, 87(10): 4727–4733.

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Access to this website is restricted to individuals who are 21 years of age or older, reside in the United States, and are qualified research professionals, institutions, or acting in an independent research capacity. All products offered on this website are sold strictly for in-vitro research use only and are not intended for human or animal consumption, clinical use, diagnostic use, or therapeutic purposes of any kind. By proceeding, you acknowledge and confirm that you meet these qualifications and understand the research-only nature and intended use of these products.