Pinealon Peptide

Overview

Pinealon (EDR) is a synthetic tripeptide bioregulator composed of the amino acid sequence Glu-Asp-Arg. Classified as one of Khavinson peptides, Pinealon is widely investigated for its potential role in gene expression, neuroprotection, cellular aging, oxidative stress regulation, and circadian rhythm research. Unlike many peptides, Pinealon has been studied for its ability to penetrate the cell and nuclear membranes, where it may interact directly with DNA and influence cellular regulatory processes.

Product Specifications

• Product Name: Pinealon (EDR)
• Other Known Titles: Glutamylaspartylarginine, T-33 Peptide
• Molecular Formula: C15H26N6O8
• Molecular Weight: 418.407 g/mol
• Sequence: Glu-Asp-Arg
• Form: Lyophilized Powder
• Application: Research Use Only

Research Overview

Pinealon has been extensively studied for its involvement in gene regulation, neuronal protection, oxidative stress, cognitive function, and healthy aging. Experimental research suggests it may influence DNA-mediated gene expression, cellular signaling pathways, and antioxidant defense mechanisms. Researchers continue investigating its potential effects on brain function, cellular survival, sleep regulation, and age-related biological processes.

Current scientific understanding is based primarily on cell-culture studies, biochemical assays, and preclinical animal research.

Mechanism of Action (Research Only)

Experimental studies suggest that Pinealon may interact directly with DNA, influencing gene expression and cellular signaling pathways. Researchers have investigated its effects on MAPK/ERK signaling, oxidative stress regulation, apoptosis, neuronal survival, and serotonin-related pathways. Additional studies continue to examine its potential role in protecting cells from hypoxia and supporting normal cellular function under experimental conditions.

Potential Research Applications

Current laboratory investigations include:

• Gene expression research
• Cellular aging studies
• Neuroprotection research
• Cognitive function
• Oxidative stress biology
• MAPK/ERK signaling
• DNA interaction studies
• Serotonin pathway research
• Circadian rhythm and sleep regulation
• Cell proliferation
• Apoptosis research
• Muscle cell biology
• Cardiovascular research
• Comparative peptide research

Storage

• Store lyophilized peptide in a cool, dry environment.
• After reconstitution, refrigerate at 2°C–8°C.
• Protect from heat, moisture, and direct light.
• Avoid repeated freeze-thaw cycles to preserve peptide stability.

Future Research

Pinealon continues to be investigated for its potential role in gene regulation, neurobiology, healthy aging, circadian rhythm, oxidative stress, and cellular regeneration. Ongoing preclinical studies aim to further understand its biological mechanisms and broader applications in laboratory science.